Fare Guide

Estimated lowest fares found within 7 days

Cheapest Airline Copa Airlines

The cheapest airline(s) flying from Santo Domingo to Panama City is Copa Airlines.

  • Copa Airlines Copa Airlines
  • Avianca Avianca
  • American Airlines American Airlines
  • United Airlines United Airlines
Cheapest Month March

Travel Period: January 2025 - December 2025

The cheapest month(s) to fly from Santo Domingo to Panama City is March.

  • Jan 2025
  • Feb 2025
  • Mar 2025
  • Apr 2025
  • May 2025
  • Jun 2025
  • Jul 2025
  • Aug 2025
  • Sep 2025
  • Oct 2025
  • Nov 2025
  • Dec 2025
Cheapest Day of the Week Monday

The cheapest day(s) of the week to fly from Santo Domingo to Panama City is Monday.

  • Sun Sunday
  • Mon Monday
  • Tue Tuesday
  • Wed Wednesday
  • Thu Thursday
  • Fri Friday
  • Sat Saturday

Flight Schedules

Last Updated: Mon, 2 Dec, 2024

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    • Airline Filter by Airline
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      • Availability
        • M
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      • 06:23 SDQ
        08:00 PTY
        2Hrs, 37m Direct
      • SDQSanto Domingo Las Americas Airport 06:23 - PTY 08:00 2h 37m Direct
      • SDQSanto Domingo Las Americas Airport 06:23
      • PTYPanama City Tocumen International Airport 08:00
      • 2h 37m
      • Direct
      • Copa Airlines (CM 108)Boeing 737 800
      • Copa Airlines (CM 108)
        • -
        • -
        • W
        • -
        • -
        • -
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      • Boeing 737 800
      • 06:23 SDQ
        08:00 PTY
        2Hrs, 37m Direct
      • SDQSanto Domingo Las Americas Airport 06:23 - PTY 08:00 2h 37m Direct
      • SDQSanto Domingo Las Americas Airport 06:23
      • PTYPanama City Tocumen International Airport 08:00
      • 2h 37m
      • Direct
      • Copa Airlines (CM 108)Boeing 737 700
      • Copa Airlines (CM 108)
        • M
        • T
        • -
        • -
        • F
        • S
        • S
      • Boeing 737 700
      • 08:53 SDQ
        10:30 PTY
        2Hrs, 37m Direct
      • SDQSanto Domingo Las Americas Airport 08:53 - PTY 10:30 2h 37m Direct
      • SDQSanto Domingo Las Americas Airport 08:53
      • PTYPanama City Tocumen International Airport 10:30
      • 2h 37m
      • Direct
      • Copa Airlines (CM 267)Boeing 737 800
      • Copa Airlines (CM 267)
        • M
        • T
        • W
        • T
        • F
        • S
        • S
      • Boeing 737 800
      • 11:53 SDQ
        13:30 PTY
        2Hrs, 37m Direct
      • SDQSanto Domingo Las Americas Airport 11:53 - PTY 13:30 2h 37m Direct
      • SDQSanto Domingo Las Americas Airport 11:53
      • PTYPanama City Tocumen International Airport 13:30
      • 2h 37m
      • Direct
      • Copa Airlines (CM 129)Boeing 737 800
      • Copa Airlines (CM 129)
        • -
        • -
        • W
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        • F
        • S
        • S
      • Boeing 737 800
      • 11:53 SDQ
        13:30 PTY
        2Hrs, 37m Direct
      • SDQSanto Domingo Las Americas Airport 11:53 - PTY 13:30 2h 37m Direct
      • SDQSanto Domingo Las Americas Airport 11:53
      • PTYPanama City Tocumen International Airport 13:30
      • 2h 37m
      • Direct
      • Copa Airlines (CM 129)Boeing 737 Max 9 Passenger
      • Copa Airlines (CM 129)
        • M
        • T
        • -
        • -
        • -
        • -
        • -
      • Boeing 737 Max 9 Passenger
      • 14:40 SDQ
        16:17 PTY
        2Hrs, 37m Direct
      • SDQSanto Domingo Las Americas Airport 14:40 - PTY 16:17 2h 37m Direct
      • SDQSanto Domingo Las Americas Airport 14:40
      • PTYPanama City Tocumen International Airport 16:17
      • 2h 37m
      • Direct
      • Copa Airlines (CM 299)Boeing 737 800
      • Copa Airlines (CM 299)
        • M
        • T
        • W
        • T
        • F
        • S
        • S
      • Boeing 737 800
      • 18:38 SDQ
        20:15 PTY
        2Hrs, 37m Direct
      • SDQSanto Domingo Las Americas Airport 18:38 - PTY 20:15 2h 37m Direct
      • SDQSanto Domingo Las Americas Airport 18:38
      • PTYPanama City Tocumen International Airport 20:15
      • 2h 37m
      • Direct
      • Copa Airlines (CM 464)Boeing 737 700
      • Copa Airlines (CM 464)
        • -
        • -
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        • T
        • -
        • -
        • -
      • Boeing 737 700
      • 18:38 SDQ
        20:15 PTY
        2Hrs, 37m Direct
      • SDQSanto Domingo Las Americas Airport 18:38 - PTY 20:15 2h 37m Direct
      • SDQSanto Domingo Las Americas Airport 18:38
      • PTYPanama City Tocumen International Airport 20:15
      • 2h 37m
      • Direct
      • Copa Airlines (CM 464)Boeing 737 800
      • Copa Airlines (CM 464)
        • M
        • T
        • -
        • -
        • -
        • -
        • S
      • Boeing 737 800
      No Schedules Sorry, there are no schedules matching your filters. Try removing one. reset
      What’s the fastest flight time from Santo Domingo to Panama City?

      The fastest flight time for direct flights from Santo Domingo to Panama City is 2 hours 37 minutes. Check latest flight schedules & prices on Wego.

      How far is Panama City from Santo Domingo?

      The flight distance between Santo Domingo and Panama City is 1479km. Check all available flights on Wego.

      When is the earliest and latest flight of the day?

      The earliest flight of the day departs at 06:23. The last flight of the day departs at 06:23. See the full list of flight times on Wego.

      How many airlines offer direct flights from Santo Domingo to Panama City?

      There are 1 airlines that offer direct flights from Santo Domingo to Panama City. Find out the list of airlines on Wego.

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